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Chemical Structure : TMX1
Catalog No.: PC-22821Not For Human Use, Lab Use Only.
TMX1 is a potent, selective, covalent JQ1-derived PROTAC degrader of BRD4 via DCAF16, functions as a molecular glue to recruit DCAF16 selectively to BRD4 BD2, causing degradation of BRD4.
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TMX1 is a potent, selective, covalent JQ1-derived PROTAC degrader of BRD4 via DCAF16, functions as a molecular glue to recruit DCAF16 selectively to BRD4 BD2, causing degradation of BRD4.
| M.Wt | 476.60 | |
| Formula | C26H28N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li Y D, et al. Cancer Research, 2023, 83(7_Supplement): 3424-3424.
2. Li YD, et al. Nat Chem Biol. 2024 Jul 29. doi: 10.1038/s41589-024-01668-4.
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