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Chemical Structure : TNIK inhibitor OBD9
Catalog No.: PC-49469Not For Human Use, Lab Use Only.
OBD9 is a small molecule TNIK inhibitor that blocks Wnt/beta-catenin signaling at the final step of transcriptional activation, suppresses colorectal cancer growth by interfering with the Wnt signaling pathway.
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OBD9 is a small molecule TNIK inhibitor that blocks Wnt/beta-catenin signaling at the final step of transcriptional activation, suppresses colorectal cancer growth by interfering with the Wnt signaling pathway.
OBD9 induces autophagic degradation of TNIK (traf2 and Nck-interacting kinase), which promotes T-cell factor-4 (TCF4)/beta-catenin–mediated gene expression.
| M.Wt | 380.40 | |
| Formula | C20H20N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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