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Chemical Structure : TNKS-IN-41
Catalog No.: PC-60367Not For Human Use, Lab Use Only.
TNKS-IN-41 is a highly potent and selective tankyrase inhibitor with pIC50 of 8.5 and 8.1 for TNKS1 and TNKS2, respectively.
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TNKS-IN-41 is a highly potent and selective tankyrase inhibitor with pIC50 of 8.5 and 8.1 for TNKS1 and TNKS2, respectively.
TNKS-IN-41 shows high selectivity over the other PARP family members.
TNKS-IN-41 induces growth inhibition of a number of tumor derived cell lines.
| M.Wt | 482.508 | |
| Formula | C24H22N10O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Thomson DW, et al. J Med Chem. 2017 Jul 13;60(13):5455-5471.
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