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Chemical Structure : TP0438836
Catalog No.: PC-35748Not For Human Use, Lab Use Only.
TP0438836 is a potent, low-absorbable sodium-dependent glucose cotransporter (SGLT) inhibitor with IC50 of 28 nM/7 nM for hSGLT1 and hSGLT2, respectively.
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TP0438836 is a potent, low-absorbable sodium-dependent glucose cotransporter (SGLT) inhibitor with IC50 of 28 nM/7 nM for hSGLT1 and hSGLT2, respectively.
TP0438836 shows a desirable PK profile in Sprague-Dawley (SD) rats and a favorable glucose-lowering effect in diabetic rats.
| M.Wt | 550.605 | |
| Formula | C27H38N2O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kuroda S, et al. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3534-3539.
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