TPO agonist 1 (PAK1-A2)

Chemical Structure : TPO agonist 1

CAS No.: 1033040-23-1

Catalog No.: PC-42122Not For Human Use, Lab Use Only.

TPO agonist 1 (PAK1-A2) is a potent, selective thrombopoietin (TPO) receptor agonist, thrombopoietin mimetic, also is an allosteric PAK1 activator with EC50 of 2.575 uM.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
25 mg	$258	In stock
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Biological Activity

TPO agonist 1 (PAK1-A2) is a potent, selective thrombopoietin (TPO) receptor agonist, thrombopoietin mimetic, also is an allosteric PAK1 activator with EC50 of 2.575 uM.

Physicochemical Properties

M.Wt	466.4946
Formula	C25H22N8O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 36 mg/mL
Chemical Name/SMILES	1H-Pyrazole-4,5-dione, 1-(3,4-dimethylphenyl)-3-methyl-, 4-[2-[2-hydroxy-3'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]hydrazone]

References

1. Patent WO2008134338A1. 2. Yu He, et al. Cell. 2026 May 28;189(11):3444-3464.e28.

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