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Chemical Structure : TRAM-34
CAS No.: 289905-88-0
Catalog No.: PC-35994Not For Human Use, Lab Use Only.
TRAM-34 (TRAM34) is a potent and highly selective blocker of intermediate conductance Ca2+-activated K+ channels (IKCa1) with Kd of 20 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $328 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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TRAM-34 (TRAM34) is a potent and highly selective blocker of intermediate conductance Ca2+-activated K+ channels (IKCa1) with Kd of 20 nM.
TRAM-34 displays 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels.
| M.Wt | 344.84 | |
| Formula | C22H17ClN2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole |
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1. Wulff H, et al. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8151-6.
2. Köhler R, et al. Circulation. 2003 Sep 2;108(9):1119-25.
3. Wulff H, et al. J Biol Chem. 2001 Aug 24;276(34):32040-5.
4. Ghanshani S, et al. J Biol Chem. 2000 Nov 24;275(47):37137-49.
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