TREX1-IN-1

Chemical Structure : TREX1-IN-1

Catalog No.: PC-25188Not For Human Use, Lab Use Only.

TREX1-IN-1 is a potent, effective inhibitor of cytosolic DNA exonuclease TREX1 (three-prime repair exonuclease 1) with IC50 of <0.1 uM for human TREX1.

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Biological Activity

TREX1-IN-1 is a potent, effective inhibitor of cytosolic DNA exonuclease TREX1 (three-prime repair exonuclease 1) with IC50 of <0.1 uM for human TREX1.

Physicochemical Properties

M.Wt	387.37
Formula	C19H18FN3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Benzimidazole-6-carboxamide, 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-1-(3-methyl-3-oxetanyl)-

References

1. Patent WO2021263079 A1 (Compound 180).

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TREX1-IN-1

Biological Activity

Physicochemical Properties

References

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