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TRV0109101

Chemical Structure : TRV0109101

CAS No.: 1401027-29-9

TRV0109101 (TRV 0109101, TRV-0109101)

Catalog No.: PC-60804Not For Human Use, Lab Use Only.

TRV0109101 is a selective, G protein-biased µ-opioid receptor (MOR) agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    TRV0109101 is a selective, G protein-biased µ-opioid receptor (MOR) agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.

    Physicochemical Properties

    M.Wt 356.528
    Formula C21H28N2OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-2-(9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)-N-(thiophen-2-ylmethyl)ethan-1-amine

    References

    1. Koblish M, et al. J Pharmacol Exp Ther. 2017 Aug;362(2):254-262.

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