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Chemical Structure : TST1N-224
Catalog No.: PC-22813Not For Human Use, Lab Use Only.
TST1N-224 is a potent inhibitor targeting the response regulator VraRC of S. aureus, inhibits the formation of the VraRC-DNA complex with IC50 of 60.2 uM, shows strong binding to VraRC (KD=23.4 uM), enhances the susceptibility of vancomycin-intermediate S. aureus (VISA) to both vancomycin and methicillin.
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TST1N-224 is a potent inhibitor targeting the response regulator VraRC of S. aureus, inhibits the formation of the VraRC-DNA complex with IC50 of 60.2 uM, shows strong binding to VraRC (KD=23.4 uM), enhances the susceptibility of vancomycin-intermediate S. aureus (VISA) to both vancomycin and methicillin.
| M.Wt | 460.62 | |
| Formula | C10H20O8S6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ying-Chu Hsu, et al. J Chem Inf Model. 2024 Jul 30. doi: 10.1021/acs.jcim.4c01046.
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