Catalog No.: PC-35820Not For Human Use, Lab Use Only.
TT-10 (YAP-TEAD activator TT-10, TAZ-K) is a small molecule activator that activates pro-proliferative YES-associated protein (YAP) and transcriptional enhancer factor domain (TEAD) activities in cardiomyocytes.
TT-10 (YAP-TEAD activator TT-10, TAZ-K) is a small molecule activator that activates pro-proliferative YES-associated protein (YAP) and transcriptional enhancer factor domain (TEAD) activities in cardiomyocytes.
TT-10 promotes cardiomyocyte proliferation and simultaneously exerts antioxidant and antiapoptotic effects in vitro via nuclear translocation of YAP, activates YAP-TEADs activity and the Wnt/β-Catenin signaling pathway.
TT-10 ameliorates cardiac dysfunction, decreases ROS and DNA aamage and apoptosis after myocardial infarction (MI) in mice.
