Catalog No.: PC-21849Not For Human Use, Lab Use Only.
TTA-Q6 is a potent, selective T-type Ca2+ channel antagonist with IC50 of 14 nM and 590 nM in FLIPR depolarized assaay and FLIPR hyperpolarized assay, respectively.
TTA-Q6 is a potent, selective T-type Ca2+ channel antagonist with IC50 of 14 nM and 590 nM in FLIPR depolarized assaay and FLIPR hyperpolarized assay, respectively. TTA-Q6 is a potent T-type Ca(2+) channel antagonist with minimized PXR activation. TTA-Q6 suppresses seizure frequency in a rat model of absence epilepsy and shows significant alterations of sleep architecture after oral dosing to rats.
