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Chemical Structure : TTP-8307
CAS No.: 950225-08-8
Catalog No.: PC-62922Not For Human Use, Lab Use Only.
TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM.
3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307.
| M.Wt | 436.49 | |
| Formula | C27H21FN4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[(1R)-1-(4-Fluorophenyl)ethyl]-3-[2-(isoquinolin-3-yl)-1H-imidazol-4-yl]benzamide |
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1. De Palma AM, et al. Antimicrob Agents Chemother. 2009 May;53(5):1850-7.
2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72.
3. Norder H, et al. Antiviral Res. 2011 Mar;89(3):204-18.
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