Chemical Structure : TTS29
CAS No.:
1082953-49-8
TTS29
Catalog No.: PC-27563Not For Human Use, Lab Use Only.
TTS29 is a small molecule inhibitor of S. typhimurium type III secretion system (T3SS), disrupts the needle assembly of Yersinia spp., P. aeruginosa and Francisella novicida, block the secretion and virulence functions of a wide array of animal and plant Gram-negative bacterial pathogens, such as Y. spp., P. aeruginosa and Francisella novicida.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
TTS29 is a small molecule inhibitor of S. typhimurium type III secretion system (T3SS), disrupts the needle assembly of Yersinia spp., P. aeruginosa and Francisella novicida, block the secretion and virulence functions of a wide array of animal and plant Gram-negative bacterial pathogens, such as Y. spp., P. aeruginosa and Francisella novicida.
Physicochemical Properties
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M.Wt
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432.49
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Formula
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C24H20N2O4S
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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(Z)-5-((Z)-4-hydroxy-3,5-dimethoxybenzylidene)-3-phenyl-2-(phenylimino)thiazolidin-4-one
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References
1. Gu L, et al. Molecules (Basel, Switzerland) 2015;20(9):17659–17674.
2. Kline T, et al. Bioorg. Med. Chem. Lett. 2009;19:1340–1343.
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