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Chemical Structure : TUG-424
CAS No.: 1082058-99-8
Catalog No.: PC-20421Not For Human Use, Lab Use Only.
TUG-424 (TUG424) is a potent, selective free fatty acid receptor 1 (FFA1, GPR40) agonist with EC50 of 32 nM, TUG-424 (100 nM) enhances glucose-stimulated insulin secretion from rat INS-1E cells and isolated mouse islets.
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|---|---|---|---|
| 5 mg | $258 | In stock | |
| 25 mg | $688 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote | ||
| 1 g | Get quote |
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TUG-424 (TUG424) is a potent, selective free fatty acid receptor 1 (FFA1, GPR40) agonist with EC50 of 32 nM, TUG-424 (100 nM) enhances glucose-stimulated insulin secretion from rat INS-1E cells and isolated mouse islets.
| M.Wt | 264.32 | |
| Formula | C18H16O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-[2-(2-Methylphenyl)ethynyl]benzenepropanoic acid |
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1. Christiansen E, et al. J Med Chem. 2008 Nov 27;51(22):7061-4.
2. Moodaley R, et al. Br J Pharmacol. 2017 Dec;174(23):4508-4522.
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