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Chemical Structure : TX-1123
Catalog No.: PC-70182Not For Human Use, Lab Use Only.
TX-1123 is a tyrphostin AG17 analog that exihibits potent Src kinase inhibitory activity with IC50 of 2.2 uM.
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TX-1123 is a tyrphostin AG17 analog that exihibits potent Src kinase inhibitory activity with IC50 of 2.2 uM.
TX-1123 also inhibits eEF2K (IC50=3.2 uM) and PKA (IC50=9.6 uM).
TX-1123 exhibits potent anti-tumor activity in HepG2 (EC50=3.66 uM) and HCT116 (EC50=39 uM) tumor cells.
| M.Wt | 312.4 | |
| Formula | C20H24O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ohkura K, et al. Anticancer Res. 2016 Jul;36(7):3645-9.
2. Hori H, et al. Bioorg Med Chem. 2002 Oct;10(10):3257-65.
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