TXA09155 | Efflux pump inhibitor | Probechem Biochemicals

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Chemical Structure : TXA09155

TXA09155 (TXA-09155)

Catalog No.: PC-26645Not For Human Use, Lab Use Only.

TXA09155 is a small molecule efflux pump inhibitor, shows synergistic effect with levofloxacin against multidrug resistant P. aeruginosa clinical isolates, shows ≥8-fold potentiation of levofloxacin, moxifloxacin, doxycycline, minocycline, cefpirome, chloramphenicol, and cotrimoxazole at 6.25 ug/mL.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	366.44
Formula	C21H23FN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(((2S,4R)-4-(aminomethyl)pyrrolidin-2-yl)methyl)-6-(4-fluorophenyl)-1H-indole-2-carboxamide

References

1. Zhang Y, et al. Antibiotics (Basel). 2022 May 26;11(6):716.

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TXA09155 (TXA-09155)

Biological Activity

Physicochemical Properties

References

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