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TXA707

Chemical Structure : TXA707

CAS No.: 1609670-89-4

TXA707 (TXA 707)

Catalog No.: PC-49166Not For Human Use, Lab Use Only.

TXA707 is the active metabolite of TXA709 and bacterial protein FtsZ inhibitor, maintains potent activity against S. aureus strains (e.g., MRSA, VRSA, DNSSA, and LNSSA) that are resistant to current SOC antibiotics.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TXA707 is the active metabolite of TXA709 and bacterial protein FtsZ inhibitor, maintains potent activity against S. aureus strains (e.g., MRSA, VRSA, DNSSA, and LNSSA) that are resistant to current SOC antibiotics.

Physicochemical Properties

M.Wt 389.300
Formula C15H8F5N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,6-difluoro-3-((6-(trifluoromethyl)thiazolo[5,4-b]pyridin-2-yl)methoxy)benzamide

References

1. Kaul M, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4845-55.

2. Lepak AJ, et al. Antimicrob Agents Chemother. 2015 Oct;59(10):6568-74.

3. Kaul M, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4290-6.

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