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Chemical Structure : TXA709
Catalog No.: PC-49164Not For Human Use, Lab Use Only.
TXA709 is a prodrug of FtsZ-targeting benzamide compound (TXA707) with enhanced metabolic stability, demonstrates improved pharmacokinetic properties, and superior in vivo antistaphylococcal efficacy (both oral and intravenous) relative to previously identified prodrugs (TXY436 and TXY541) of PC190723.
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TXA709 is a prodrug of FtsZ-targeting benzamide compound (TXA707) with enhanced metabolic stability, demonstrates improved pharmacokinetic properties, and superior in vivo antistaphylococcal efficacy (both oral and intravenous) relative to previously identified prodrugs of PC190723.
| M.Wt | 514.471 | |
| Formula | C22H19F5N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kaul M, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4845-55.
2. Lepak AJ, et al. Antimicrob Agents Chemother. 2015 Oct;59(10):6568-74.
3. Kaul M, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4290-6.
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