TXH1033 | FtsZ inhibitor | Probechem Biochemicals

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Chemical Structure : TXH1033

TXH1033 (TXH-1033)

Catalog No.: PC-25155Not For Human Use, Lab Use Only.

TXH1033 is the orally active, carboxamide prodrug of TXH9179, which is a next-generation benzamide-based FtsZ inhibitor, TXH1033 is rapidly hydrolyzed to TXH9179 by serum acetylcholinesterases, exhibited in vivo efficacyin mouse model of systemic (peritonitis) MRSA infection.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	470.49
Formula	C23H20F2N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-((6-ethynylthiazolo[5,4-b]pyridin-2-yl)methoxy)-2,6-difluorobenzoyl)-1-methylpiperidine-4-carboxamide

References

1. Eric Bryan, et al. ACS Chem Biol. 2023 Mar 17;18(3):629-642.

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TXH1033 (TXH-1033)

Biological Activity

Physicochemical Properties

References

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