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TXY541

Chemical Structure : TXY541

CAS No.: 1499168-63-6

TXY541 (TXY 541)

Catalog No.: PC-49165Not For Human Use, Lab Use Only.

TXY541 is a 1-methylpiperidine-4-carboxamide prodrug of PC190723 and bacterial protein FtsZ inhibitor, TXY541 is efficacious in vivo in mouse models of systemic infection with both methicillin-sensitive and methicillin-resistant S. aureus.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    TXY541 is a 1-methylpiperidine-4-carboxamide prodrug of PC190723 and bacterial protein FtsZ inhibitor, TXY541 is efficacious in vivo in mouse models of systemic infection with both methicillin-sensitive and methicillin-resistant S. aureus.

    Physicochemical Properties

    M.Wt 480.915
    Formula C21H19ClF2N4O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3-((6-chlorothiazolo[5,4-b]pyridin-2-yl)methoxy)-2,6-difluorobenzoyl)-1-methylpiperidine-4-carboxamide

    References

    1. Kaul M, et al. Biochem Pharmacol. 2013 Dec 15;86(12):1699-707.

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