Chemical Structure : Tadalafil
CAS No.: 171596-29-5
Catalog No.: PC-46014Not For Human Use, Lab Use Only.
Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).
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Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).
Tadalafil shows no inhibition on most of the other families of PDEs, with the exception of PDE11.
M.Wt | 389.404 | |
Formula | C22H19N3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 52 mg/mL |
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Chemical Name/SMILES |
Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)- |
1. Blount MA, et al. Mol Pharmacol, 2004, 66(1), 144-152.
2. Ring BJ, et al. Clin Pharmacol Ther, 2005, 77(1), 63-75.
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