Tadalafil (IC-351) | PDE5 inhibitor | Probechem Biochemicals

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Chemical Structure : Tadalafil

CAS No.: 171596-29-5

Tadalafil (IC-351, IC351)

Catalog No.: PC-46014Not For Human Use, Lab Use Only.

Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).

Packing	Price	Stock
50 mg	$88	In stock
100 mg	$128	In stock
200 mg	$188	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).
Tadalafil shows no inhibition on most of the other families of PDEs, with the exception of PDE11.

Physicochemical Properties

M.Wt	389.404
Formula	C22H19N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 52 mg/mL
Chemical Name/SMILES	Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-

References

1. Blount MA, et al. Mol Pharmacol, 2004, 66(1), 144-152.

2. Ring BJ, et al. Clin Pharmacol Ther, 2005, 77(1), 63-75.

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Tadalafil (IC-351, IC351)

Biological Activity

Physicochemical Properties

References

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