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Tamuzimod

Chemical Structure : Tamuzimod

CAS No.: 2097854-81-2

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Tamuzimod (VTX002, VTX-002)

Catalog No.: PC-24944Not For Human Use, Lab Use Only.

Tamuzimod (VTX002) is a peripherally-restricted, potent and selective, orally bioavailable small molecule modulator of sphingosine-1-phosphate-1 receptor (S1PR1, S1P1 receptor) in development for the treatment of ulcerative colitis (UC).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Tamuzimod (VTX002) is a peripherally-restricted, potent and selective, orally bioavailable small molecule modulator of sphingosine-1-phosphate-1 receptor (S1PR1, S1P1 receptor) in development for the treatment of ulcerative colitis (UC).

Physicochemical Properties

M.Wt 546.71
Formula C21H13Cl3F3N5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Piperidinone, 5-[2,5-dichloro-4-[5-[8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-, (5R)-

References

1. Patent WO2018211324 A1.

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