Chemical Structure : Taniborbactam hydrochloride
CAS No.: 2244235-49-0
Catalog No.: PC-23182Not For Human Use, Lab Use Only.
Taniborbactam (VNRX5133) hydrochloride is a highly potent and specific beta-lactamase inhibitor with IC50 of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2 respectively.
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Taniborbactam (VNRX5133) hydrochloride is a highly potent and specific beta-lactamase inhibitor with IC50 of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2 respectively.
Taniborbactam (VNRX5133) shows activity against Gram-negative bacteria and used in combination with a licensed beta-lactam antibiotic.
M.Wt | 462.18 | |
Formula | C19H28BN3O5.2ClH | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2H-1,2-Benzoxaborin-8-carboxylic acid, 3-[[2-[trans-4-[(2-aminoethyl)amino]cyclohexyl]acetyl]amino]-3,4-dihydro-2-hydroxy-, hydrochloride (1:2), (3R)- |
1. Krajnc A, et al. J Med Chem. 2019 Sep 26;62(18):8544-8556.
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