Chemical Structure : Taprenepag isopropyl
CAS No.: 1005549-94-9
Catalog No.: PC-28387Not For Human Use, Lab Use Only.
Taprenepag isopropyl (PF-04217329) is the prodrug of Taprenepag (CP-544326), a potent and selective prostaglandin EP2 receptor agonist with IC50 of 10 nM and EC50 of 2.8 nM.
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| 25 mg | $148 | In stock | |
| 50 mg | $248 | In stock | |
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Taprenepag isopropyl (PF-04217329) is the prodrug of Taprenepag (CP-544326), a potent and selective prostaglandin EP2 receptor agonist with IC50 of 10 nM and EC50 of 2.8 nM.
Taprenepag isopropyl (PF-04217329) shows increased corneal permeability and ocular bioavailability.
Taprenepag isopropyl (PF-04217329) causes sustained intraocular pressure (IOP) reduction, is a clinical candidate for treatment of glaucoma and ocular hypertension.
| M.Wt | 520.60 | |
| Formula | C27H28N4O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Isopropyl 2-(3-((N-(4-(1H-pyrazol-1-yl)benzyl)pyridine-3-sulfonamido)methyl)phenoxy)acetate |
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1. Prasanna G, et al. Exp Eye Res. 2011 Sep;93(3):256-64.
2. Schachar RA, et al. Curr Eye Res. 2011 Sep;36(9):809-17.
3. Qu C, et al. Sci Adv. 2021 Apr 2;7(14):eabf1268.

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