Targaprimir-96 | miR-96 modualtor | Probechem Biochemicals

Chemical Structure : Targaprimir-96

Targaprimir-96 (Targaprimir96)

Catalog No.: PC-70308Not For Human Use, Lab Use Only.

Targaprimir-96 is a small molecule that selectively modulates miR-96 production in cancer cells and triggers apoptosis.

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Biological Activity

Targaprimir-96 is a small molecule that selectively modulates miR-96 production in cancer cells and triggers apoptosis.
Targaprimir-96 directly engages pri-miR-96 in breast cancer cells, and has a favorable pharmacokinetic profile and decreases tumor burden in a mouse model of triple-negative breast cancer.

Physicochemical Properties

M.Wt	1391.75
Formula	C77H102N18O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-((2-((2-amino-2-oxoethyl)((1-(3-(4-(2,6-di-tert-butyl-4-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)phenoxy)butanamido)propyl)-1H-1,2,3-triazol-4-yl)methyl)amino)-2-oxoethyl)(propyl)amino)-2-oxoethyl)-4-(3-(6-(4-methylpiperazin-1-yl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-2'-yl)phenoxy)-N-propylbutanamide

References

1. Velagapudi SP, et al. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5898-903.

Targaprimir-96 (Targaprimir96)

Biological Activity

Physicochemical Properties

References

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