Tarocin A

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Chemical Structure : Tarocin A

Catalog No.: PC-24737Not For Human Use, Lab Use Only.

Tarocin A is a specific inhibitor of UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (TarO) with IC50 of 0.18 uM, inhibits the first step in wall teichoic acid biosynthesis, restore β-lactam efficacy against MRSA.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	481.39
Formula	C24H17F6NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-3-(2-(naphthalen-1-yl)acetyl)oxazolidin-2-one

References

1. Lee SH, et al. Sci Transl Med. 2016 Mar 9;8(329):329ra32.

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Tarocin A

Biological Activity

Physicochemical Properties

References

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