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Taspoglutide

Chemical Structure : Taspoglutide

CAS No.: 275371-94-3

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Taspoglutide (ITM-077, R-1583, BIM-51077)

Catalog No.: PC-47502Not For Human Use, Lab Use Only.

Taspoglutide (ITM-077, R-1583, BIM-51077) is a glucagon-like peptide-1(GLP-1) agonist with EC50 of 0.06 nM, shows potential for treatment of type 2 diabetes.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Taspoglutide (ITM-077, R-1583, BIM-51077) is a glucagon-like peptide-1(GLP-1) agonist with EC50 of 0.06 nM, shows potential for treatment of type 2 diabetes.
Phase III clinical trials halted due to incidences of side effects.

Physicochemical Properties

M.Wt 3339.709
Formula C152H232N40O45
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

DMSO: ≥ 28 mg/mL
Chemical Name/SMILES

7-36-Glucagon-like peptide I (human), 8-(2-methylalanine)-35-(2-methylalanine)-36-L-argininamide-

References

1. Dong JZ, et al. Diabetes Obes Metab. 2011 Jan;13(1):19-25.

2. Giraudon M, et al. Diabetes Obes Metab. 2017 Apr;19(4):537-544.

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