Chemical Structure : Tasquinimod
CAS No.:
254964-60-8
Tasquinimod
(ABR-215050;ABR215050;ABR 215050)
Catalog No. : PC-42638Not For Human Use, Lab Use Only.
An orally active antiangiogenic agent with anti-prostate cancer activity, an allosteric modulator of HDAC4 with Kd of 10-30 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4263801
Biological Activity
Tasquinimod (ABR215050) is an orally active antiangiogenic agent with anti-prostate cancer activity, an allosteric modulator of HDAC4 with Kd of 10-30 nM.S100A9 inhibitor.
Physicochemical Properties
M.Wt
406.3552
Formula
C20H17F3N2O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 42 mg/mL
Chemical Name/SMILES
3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-
References
1. Isaacs JT, et al. Prostate.
2. Olsson A, et al. Mol Cancer
3. Dalrymple SL, et al. Prostate
4. Isaacs JT, et al. Cancer Res.
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