Chemical Structure : Tec Kinase-IN-14
Catalog No.: PC-60853Not For Human Use, Lab Use Only.
A selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 7.0 uM.
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Tec Kinase-IN-14 is a selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 7.0 uM.
Tec Kinase-IN-14 inhibits Tec-FGF2 complex and blocks tyrosine phosphorylation of FGF2 in cells, also inhibit FGF2 secretion from cells.
M.Wt | 418.247 | |
Formula | C18H16BrN3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. La Venuta G, et al. J Biol Chem. 2016 Aug 19;291(34):17787-803.
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