Tec Kinase-IN-14 |CAS:852838-07-4 Probechem Biochemicals

Chemical Structure : Tec Kinase-IN-14

Tec Kinase-IN-14

Catalog No.: PC-60853Not For Human Use, Lab Use Only.

A selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 7.0 uM.

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Biological Activity

Tec Kinase-IN-14 is a selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 7.0 uM.
Tec Kinase-IN-14 inhibits Tec-FGF2 complex and blocks tyrosine phosphorylation of FGF2 in cells, also inhibit FGF2 secretion from cells.

Physicochemical Properties

M.Wt	418.247
Formula	C18H16BrN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(7-bromo-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylate

References

1. La Venuta G, et al. J Biol Chem. 2016 Aug 19;291(34):17787-803.

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Tec Kinase-IN-14

Biological Activity

Physicochemical Properties

References

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