Tec Kinase-IN-21 |CAS:931664-41-4 Probechem Biochemicals

Chemical Structure : Tec Kinase-IN-21

Tec Kinase-IN-21

Catalog No.: PC-60854Not For Human Use, Lab Use Only.

Tec Kinase-IN-21 is a selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 11.7 uM.

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Biological Activity

Tec Kinase-IN-21 is a selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 11.7 uM.
Tec Kinase-IN-21 inhibits Tec-FGF2 complex and blocks tyrosine phosphorylation of FGF2 in cells, also inhibit FGF2 secretion from cells.

Physicochemical Properties

M.Wt	362.832
Formula	C16H15ClN4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-((6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)thio)ethan-1-one

References

1. La Venuta G, et al. J Biol Chem. 2016 Aug 19;291(34):17787-803.

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Tec Kinase-IN-21

Biological Activity

Physicochemical Properties

References

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