Tec Kinase-IN-6 |CAS:923762-87-2 Probechem Biochemicals

Chemical Structure : Tec Kinase-IN-6

Tec Kinase-IN-6

Catalog No.: PC-60852Not For Human Use, Lab Use Only.

Tec Kinase-IN-6 is a selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM.

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Biological Activity

Tec Kinase-IN-6 is a selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM.
Tec Kinase-IN-6 inhibits Tec-FGF2 complex and blocks tyrosine phosphorylation of FGF2 in cells, also inhibit FGF2 secretion from cells.

Physicochemical Properties

M.Wt	369.377
Formula	C19H19N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-methyl 2-((6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl) 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate

References

1. La Venuta G, et al. J Biol Chem. 2016 Aug 19;291(34):17787-803.

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Tec Kinase-IN-6

Biological Activity

Physicochemical Properties

References

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