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Tec Kinase-IN-6

Chemical Structure : Tec Kinase-IN-6

CAS No.: 923762-87-2

Tec Kinase-IN-6

Catalog No.: PC-60852Not For Human Use, Lab Use Only.

Tec Kinase-IN-6 is a selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Tec Kinase-IN-6 is a selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM.
    Tec Kinase-IN-6 inhibits Tec-FGF2 complex and blocks tyrosine phosphorylation of FGF2 in cells, also inhibit FGF2 secretion from cells.

    Physicochemical Properties

    M.Wt 369.377
    Formula C19H19N3O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-methyl 2-((6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl) 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate

    References

    1. La Venuta G, et al. J Biol Chem. 2016 Aug 19;291(34):17787-803.

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