Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Tecovirimat
CAS No.: 869572-92-9
Catalog No.: PC-35382Not For Human Use, Lab Use Only.
Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses.
Tecovirimat (ST-246) is active against multiple orthopoxviruses, including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), and variola viruse.
Tecovirimat (ST-246) inhibits the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping.
| M.Wt | 376.335 | |
| Formula | C19H15F3N2O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(f)isoindol-2(1H)-yl)-benzamide |
|
1. Yang G, et al. J Virol. 2005 Oct;79(20):13139-49.
2. Quenelle DC, et al. Antimicrob Agents Chemother. 2007 Feb;51(2):689-95.
3. Bailey TR, et al. J Med Chem. 2007 Apr 5;50(7):1442-4.
4. Quenelle DC, et al. Antimicrob Agents Chemother. 2007 Nov;51(11):4118-24.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
