Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Telotristat
CAS No.: 1033805-28-5
Catalog No.: PC-43357Not For Human Use, Lab Use Only.
Telotristat (LP-778902) is a potent, small-molecule inhibitor of peripheral serotonin synthesis, acts by inhibiting tryptophan hydroxylase (TPH) with IC50 of 28 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | $548 | In stock | |
| 250 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Telotristat (LP-778902) is a potent, small-molecule inhibitor of peripheral serotonin synthesis, acts by inhibiting tryptophan hydroxylase (TPH) with IC50 of 28 nM.
Telotristat (LP-778902) demonstrates potential for the treatment of carcinoid syndrome.
| M.Wt | 546.9288 | |
| Formula | C25H22ClF3N6O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
L-Phenylalanine, 4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]- |
|
1. Margolis KG, et al. Gut. 2014 Jun;63(6):928-37.
2. Kulke MH, et al. Endocr Relat Cancer. 2014 Oct;21(5):705-14.
3. Kulke MH, et al. J Clin Oncol. 2017 Jan;35(1):14-23.
4. Kim JJ, et al. Am J Physiol Gastrointest Liver Physiol.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
