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Temozolomide

Chemical Structure : Temozolomide

CAS No.: 85622-93-1

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Temozolomide (NSC362856, CCRG-8104, TZM)

Catalog No.: PC-45183Not For Human Use, Lab Use Only.

Temozolomide (NSC362856, CCRG-8104, TZM) is an alkylating agent used as a treatment of some brain cancers, astrocytoma and glioblastoma.

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50 mg $58 In stock
100 mg $78 In stock
500 mg $128 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Temozolomide (NSC362856, CCRG-8104, TZM) is an alkylating agent used as a treatment of some brain cancers, astrocytoma and glioblastoma.
Temozolomide is a prodrug and an imidazotetrazine derivative of the alkylating agent dacarbazine.

Physicochemical Properties

M.Wt 194.1508
Formula C6H6N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

DMSO: ≥ 33.33 mg/mL
Chemical Name/SMILES

Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-

References

1. Rao JU, et al. Sci Rep. 2017 Aug 11;7(1):7865.

2. Tateishi K, et al. Cancer Res. 2017 Aug 1;77(15):4102-4115.

3. Beier D, et al. Cancer Res. 2008 Jul 15;68(14):5706-15.

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