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Tenatoprazole

Chemical Structure : Tenatoprazole

CAS No.: 113712-98-4

Tenatoprazole (TU-199, TU199)

Catalog No.: PC-23331Not For Human Use, Lab Use Only.

Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor, inhibits gastric H+/K+-ATPase activity with IC50 of 6.2 uM, also inhibits glutathione peroxidase 1 (GPX1).

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Biological Activity

Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor, inhibits gastric H+/K+-ATPase activity with IC50 of 6.2 uM, also inhibits glutathione peroxidase 1 (GPX1).

Physicochemical Properties

M.Wt 346.41
Formula C16H18N4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-imidazo[4,5-b]pyridine

References

1. Thomson AB, et al. Aliment Pharmacol Ther. 2006;23(8):1179-1187.

2. Uchiyama K, et al. Methods Find Exp Clin Pharmacol. 1999;21(2):115-122.

3. Dorian M Cheff, et al. Redox Biol. 2023 Jul:63:102719.

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