Chemical Structure : Ternatin
CAS No.:
148619-41-4
Ternatin
Catalog No.: PC-28176Not For Human Use, Lab Use Only.
Ternatin is a highly N-methylated cyclic heptapeptide and potent inhibitor of fat accumulation against 3T3-L1 murine adipocytes with EC50 of 0.14 ug/mL, shows antiperoxidative effect against lipid peroxidation, targets eukaryotic elongation factor-1A (eEF1A) and inhibits protein synthesis, shows cytotoxicity to cancer cells.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
Ternatin is a highly N-methylated cyclic heptapeptide and potent inhibitor of fat accumulation against 3T3-L1 murine adipocytes with EC50 of 0.14 ug/mL, shows antiperoxidative effect against lipid peroxidation, targets eukaryotic elongation factor-1A (eEF1A) and inhibits protein synthesis, shows cytotoxicity to cancer cells.
Physicochemical Properties
|
M.Wt
|
737.97
|
|
Formula
|
C37H67N7O8
|
|
Appearance
|
Solid
|
|
CAS No.
|
|
|
Storage
|
- Solide Powder
-
-20°C 12 Months; 4°C 6 Months
|
- In Solvent
-
-80°C 6 Months; -20°C 6 Months
|
|
Shipping
|
|
|
Solubility
|
10 mM in DMSO
|
|
Chemical Name/SMILES
|
Cyclo[N-methyl-L-alanyl-N-methyl-D-alanyl-(3R)-3-hydroxy-D-leucyl-D-alloisoleucyl-N-methyl-L-alanyl-N-methyl-L-leucyl-L-leucyl]
|
References
1. Shimokawa K, et al. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4447-9.
2. Souza MF, et al. Phytomedicine. 1997 Mar;4(1):27-31.
3. Carelli JD, et al. Elife. 2015 Dec 10;4:e10222.
Contact Us
sales@probechem.com
