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Tertiapin-Q

Chemical Structure : Tertiapin-Q

CAS No.: 910044-56-3

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Tertiapin-Q

Catalog No.: PC-22937Not For Human Use, Lab Use Only.

Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and renal outer medullary potassium channel (ROMK1, Kir1.1), blocks recombinant and native large conductance K+ channels.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and renal outer medullary potassium channel (ROMK1, Kir1.1), blocks recombinant and native large conductance K+ channels.

Physicochemical Properties

M.Wt 2452.00
Formula C106H175N35O24S4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridge: Cys3-Cys14, Cys5-Cys18)

References

1. Picton LD, et al. Sci Rep. 2016 Oct 20;6:35749.

2. Sackin H, et al. Biophys J. 2003 Feb;84(2 Pt 1):910-21.

3. Jin W, et al. Biochemistry. 1999 Oct 26;38(43):14294-301.

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