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Tetomilast

Chemical Structure : Tetomilast

CAS No.: 145739-56-6

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Tetomilast (OPC-6535, OPC6535)

Catalog No.: PC-63093Not For Human Use, Lab Use Only.

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release.
Tetomilast attenuates sepsis-induced acute lung injury.

Physicochemical Properties

M.Wt 370.42
Formula C19H18N2O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid

References

1. Schreiber S, et al. Gastroenterology. 2007 Jan;132(1):76-86.

2. Bloomfield GL, et al. J Surg Res. 1997 Sep;72(1):70-7.

3. Ejiri S, et al. Transplant Proc. 2000 Mar;32(2):318-21.

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