Tetrabenazine | VMAT2 inhibitor | Probechem Biochemicals

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Chemical Structure : Tetrabenazine

CAS No.: 58-46-8

Tetrabenazine (Ro 1-9569)

Catalog No.: PC-24214Not For Human Use, Lab Use Only.

Tetrabenazine (Ro 1-9569) is a potent, reversible inhibitor of the vesicular monoamine transporter VMAT2 with Kd of 1.34 nM, shows potential for diseases related to hyperactive movement disorders such as Huntington's disease.

Packing	Price	Stock
50 mg	$38	In stock
100 mg	$58	In stock
500 mg	$98	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	317.43
Formula	C19H27NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	rel-(3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one

References

1. J C Shih, et al. Brain Res. 1999 Jul 24;835(2):104-12.

2. Nobue Kitanaka, et al. Pharmacol Biochem Behav. 2018 Sep;172:9-16.

3. S J Podurgiel, et al. Neuroscience. 2013 Oct 10;250:507-19.

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Tetrabenazine (Ro 1-9569)

Biological Activity

Physicochemical Properties

References

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