Catalog No.: PC-62318Not For Human Use, Lab Use Only.
Tetrandrine (NSC 77037, Fanchinine) is a bis-benzylisoquinoline alkaloid that acts a calcium channel blocker (IC50= 8 and 20 uM for L-type and T-type calcium channels, respectively) and induces apoptosis.
Tetrandrine (NSC 77037, Fanchinine) is a bis-benzylisoquinoline alkaloid that acts a calcium channel blocker (IC50= 8 and 20 uM for L-type and T-type calcium channels, respectively) and induces apoptosis.
Tetrandrine produces anti-inflammatory, immunomodulating, anti-proliferative, and free radical scavenging effects.
Tetrandrine has also been shown to increase glucose utilization by enhancing hepatocyte glycogen synthesis.
Tetrandrine is a potent cell autophagy agonist, is also a potent CAMKIIdelta inhibitor.
Physicochemical Properties
M.Wt
622.8
Formula
C38H42N2O6
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
d-tetrandrine
References
1. Xie QM, et al. Acta Pharmacol Sin. 2002 Dec;23(12):1107-13.
