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Chemical Structure : Tezampanel
Catalog No.: PC-61713Not For Human Use, Lab Use Only.
Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor.
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Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor.
Tezampanel (LY 293558, NGX 424) has neuroprotective and anticonvulsant properties, also has anxiolytic effects in animal studies.
| M.Wt | 279.344 | |
| Formula | C13H21N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ornstein PL, et al. J Med Chem. 1993 Jul 9;36(14):2046-8.
2. LeBlanc MH, et al. Stroke. 1995 Oct;26(10):1908-14; discussion 1914-5.
3. Benvenga MJ, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):164-70.
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