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Thailanstatin A

Chemical Structure : Thailanstatin A

CAS No.: 1426953-21-0

Thailanstatin A (TST-A)

Catalog No.: PC-38056Not For Human Use, Lab Use Only.

Thailanstatin A (TST-A) is a potent antiproliferative natural product, a pre-mRNA splicing inhibitor and antiproliferative agent..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Thailanstatin A (TST-A) is a potent antiproliferative natural product, a pre-mRNA splicing inhibitor and antiproliferative agent.

Physicochemical Properties

M.Wt 535.634
Formula C28H41NO9
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[(3R,4R,5R,7S)-5-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(Z,4S)-4-acetyloxypent-2-enoyl]amino]-3,6-dimethyloxan-2-yl]-3-methylpenta-1,3-dienyl]-4-hydroxy-1,6-dioxaspiro[2.5]octan-7-yl]acetic acid

References

1. Liu X, et al. J Nat Prod. 2013 Apr 26;76(4):685-93.

2. Puthenveetil S, et al. Bioconjug Chem. 2016 Aug 17;27(8):1880-8.

3. Nicolaou KC, et al. J Am Chem Soc. 2016 Jun 22;138(24):7532-5.

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