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Thailanstatin C

Chemical Structure : Thailanstatin C

CAS No.: 1426953-24-3

Thailanstatin C (TST-C)

Catalog No.: PC-38057Not For Human Use, Lab Use Only.

Thailanstatin C (TST-C) is a potent antiproliferative natural product, a pre-mRNA splicing inhibitor and antiproliferative agent..

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Biological Activity

Thailanstatin C (TST-C) is a potent antiproliferative natural product, a pre-mRNA splicing inhibitor and antiproliferative agent.

Physicochemical Properties

M.Wt 600.14
Formula C30H46ClNO9
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((2S,4S,5R,6R)-4-(chloromethyl)-4,5-dihydroxy-6-((1E,3E)-5-((2S,3S,5R,6R)-5-((S,Z)-4-(isobutyryloxy)pent-2-enamido)-3,6-dimethyltetrahydro-2H-pyran-2-yl)-3-methylpenta-1,3-dien-1-yl)tetrahydro-2H-pyran-2-yl)acetic acid

References

1. Liu X, et al. J Nat Prod. 2013 Apr 26;76(4):685-93.

2. Puthenveetil S, et al. Bioconjug Chem. 2016 Aug 17;27(8):1880-8.

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