Catalog No.: PC-28124Not For Human Use, Lab Use Only.
Theophylline (1,3-Dimethylxanthine) is a non-selective oral phosphodiesterase (PDE) inhibitor, is also a adenosine receptor antagonist and histone deacetylase (HDAC) activator, inhibits PDE3 activity to relax airway smooth muscle, also has anti-inflammatory activity by increase IL-10 and inhibits NF-κB, induces apoptosis.
Theophylline (1,3-Dimethylxanthine) is a non-selective oral phosphodiesterase (PDE) inhibitor, is also a adenosine receptor antagonist and histone deacetylase (HDAC) activator, inhibits PDE3 activity to relax airway smooth muscle, also has anti-inflammatory activity by increase IL-10 and inhibits NF-κB, induces apoptosis.
Physicochemical Properties
M.Wt
180.17
Formula
C7H8N4O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1,3-Dimethyl-1H-purine-2,6(3H,9H)-dione
References
1. Katz S, et al. Br J Pharmacol. 1973 Jul;48(3):505-15.
2. Uzunov P, et al. Acta Neurobiol Exp (Wars). 1975;35(2):159-64.
3. Haliotis T, et al. J Natl Cancer Inst. 1984 May;72(5):991-8.
