Chemical Structure : Tiagabine hydrochloride
CAS No.: 145821-59-6
Catalog No.: PC-24080Not For Human Use, Lab Use Only.
Tiagabine hydrochloride is an anticonvulsant agent and selective inhibitor of
GABA transporter 1 (GAT1) with Ki of 0.1 uM, potently and selectively inhibits GABA reuptake with IC50 of 67, 446 and 182 nM for [3H]GABA uptake in synaptosomes, neurons and glia, respectively.
Packing | Price | Stock | Quantity |
---|---|---|---|
10 mg | $48 | In stock | |
50 mg | $98 | In stock | |
100 mg | $148 | In stock | |
250 mg | Get quote |
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Tiagabine hydrochloride is an anticonvulsant agent and selective inhibitor of
GABA transporter 1 (GAT1) with Ki of 0.1 uM, potently and selectively inhibits GABA reuptake with IC50 of 67, 446 and 182 nM for [3H]GABA uptake in synaptosomes, neurons and glia, respectively.
M.Wt | 412.00 | |
Formula | C20H26ClNO2S2 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(R)-1-(4,4-Bis(3-methylthiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride |
1. Braestrup C, et al. J Neurochem. 1990 Feb;54(2):639-47.
2. Henjum S, Neurochem Int. 2007 Jan;50(2):365-70.
3. Sheehan DV, et al. Psychopharmacol Bull. 2007;40(3):32-40.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright