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Tildacerfont

Chemical Structure : Tildacerfont

CAS No.: 1014983-00-6

Tildacerfont (SPR001, LY2371712)

Catalog No.: PC-35469Not For Human Use, Lab Use Only.

Tildacerfont (SPR001, LY2371712) is a novel corticotropin releasing factor (CRF) CRF1 receptor antagonist, effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels.

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Biological Activity

Tildacerfont (SPR001, LY2371712) is a novel corticotropin releasing factor (CRF) CRF1 receptor antagonist, effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels.

Physicochemical Properties

M.Wt 419.972
Formula C20H26ClN5OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[4-chloro-2-(morpholin-4-yl)-1,3-thiazol-5-yl]-2,5-dimethyl-7-(pentan-3-yl)pyrazolo[1,5-a]pyrimidine

References

1. Prete A, et al. Eur J Endocrinol. 2021;186(1):R1-R14.

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