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Chemical Structure : Tipranavir
CAS No.: 174484-41-4
Catalog No.: PC-21699Not For Human Use, Lab Use Only.
Tipranavir (PNU-140690) is a potent, nonpeptidic and orally bioavailable HIV protease inhibitor with Ki vaule of 8 pM, shows an IC90 value of 100 nM in antiviral cell culture.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $188 | In stock | |
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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Tipranavir (PNU-140690) is a potent, nonpeptidic and orally bioavailable HIV protease inhibitor with Ki vaule of 8 pM, shows an IC90 value of 100 nM in antiviral cell culture.
Tipranavir (PNU-140690) has excellent potency against a variety of HIV type 1 (HIV-1) laboratory strains and clinical isolates, including those resistant to the reverse transcriptase inhibitors zidovudine or delavirdine.
Tipranavir (PNU-140690) contributes to synergistic antiviral activity, when combined with either zidovudine or delavirdine.
Tipranavir (PNU-140690) is also highly active against HIV-1 variants resistant to peptidomimetic protease inhibitors.
| M.Wt | 602.67 | |
| Formula | C31H33F3N2O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
rel-N-(3-((R)-1-((R)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)propyl)phenyl)-5-(trifluoromethyl)pyridine-2-sulfonamide |
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1. Turner SR, et al. J Med Chem. 1998 Aug 27;41(18):3467-76.
2. Poppe SM, et al. Antimicrob Agents Chemother. 1997 May;41(5):1058-63.
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