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Tislelizumab

Chemical Structure : Tislelizumab

CAS No.:

Tislelizumab (Anti-human PD-1 mAb, human IgG4P-Kappa; BGB-A317)

Catalog No.: PC-Ab1067Not For Human Use, Lab Use Only.

Tislelizumab (BGB-A317) is a humanized IgG4 anti-PD-1 monoclonal antibody specifically designed to minimize binding to FcγR on macrophages. Tislelizumab (BGB-A317) binds to and blocks human PD-1 with high affinity and specificity, shows anti-tumor activity through activation of antibody-dependent macrophage-mediated killing of T effector cells..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Tislelizumab (BGB-A317) is a humanized IgG4 anti-PD-1 monoclonal antibody specifically designed to minimize binding to FcγR on macrophages. Tislelizumab (BGB-A317) binds to and blocks human PD-1 with high affinity and specificity, shows anti-tumor activity through activation of antibody-dependent macrophage-mediated killing of T effector cells.

Physicochemical Properties

M.Wt
Formula Human IgG4P-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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