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Tonabersat

Chemical Structure : Tonabersat

CAS No.: 175013-84-0

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Tonabersat (SB-220453, SB220453)

Catalog No.: PC-21795Not For Human Use, Lab Use Only.

SB-220453 (Tonerbasat) is a potential antimigraine agent and gap-junction modulator, demonstrates activity as a gap-junction inhibitor in animal studies.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB-220453 (Tonerbasat) is a potential antimigraine agent and gap-junction modulator, demonstrates activity as a gap-junction inhibitor in animal studies.

Physicochemical Properties

M.Wt 391.82
Formula C20H19ClFNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-3-chloro-4-fluorobenzamide

References

1. Chan WN, et al. Bioorg Med Chem Lett. 1999 Jan 18;9(2):285-90.

2. Read SJ, et al. Cephalalgia. 2000 Mar;20(2):92-9.

3. Parsons AA, et al. Br J Pharmacol. 2001 Apr;132(7):1549-57.

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