Topiroxostat (FYX-051) | XOR inhibitor

Chemical Structure : Topiroxostat

CAS No.: 577778-58-6

Topiroxostat (FYX-051, FYX051)

Catalog No.: PC-20358Not For Human Use, Lab Use Only.

Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM.

Packing	Price	Stock
50 mg	$98	In stock
100 mg	$148	In stock
250 mg	$258	In stock
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Biological Activity

Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM.
Topiroxostat (FYX-051) exhibits extremely potent effect in lowering the serum uric acid (UA) levels in vivo and has good pharmacokinetic properties.

Physicochemical Properties

M.Wt	248.25
Formula	C13H8N6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole

References

1. Sato T, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9.

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Topiroxostat (FYX-051, FYX051)

Biological Activity

Physicochemical Properties

References

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