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Topiroxostat

Chemical Structure : Topiroxostat

CAS No.: 577778-58-6

Topiroxostat (FYX-051, FYX051)

Catalog No.: PC-20358Not For Human Use, Lab Use Only.

Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM.
Topiroxostat (FYX-051) exhibits extremely potent effect in lowering the serum uric acid (UA) levels in vivo and has good pharmacokinetic properties.

Physicochemical Properties

M.Wt 248.25
Formula C13H8N6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole

References

1. Sato T, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9.

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